Mannitol

H.S. Code:29054300
Specification:BP/USP
Appearance:White crystal powder

Application:

1. Injection material: used in producing the mannitol injection solution, reducing the encephalic pressure, the intraocular pressure etc.

2. Excipient of filler for tablets: used in the anticancer drug, antibacterial, antihistamine medicine, in vietmin, drunk awaking drug, the mouth freshener tablet and so on.

3. Vasodilator medicine for blood vessel of brain: used in treating the blood vessel blocked brain.

4. Diuretic stuff: mannitol is a kind of mild laxative lapactic, which has a special curative effect to oliguria and the kidney function failure caused by dropsy, burnt and so on.

Specification:

Items	Specification	Results
Appearance	White crystal powder;scentless,sweet,dissolve easily in water,slightly in alcohol and hardly dissolve in ether	Conforms
Solubility	Soluble in water, slightly soluble in ethanol	Conforms
Melting Point	166-170°C	166.2-167.5°C
Identification	Conforms to the standard	conforms
Chloride	≤0.003%	<0.003%
Clarity and color of solution	Conformed to the standard	Conforms
Oxalate	≤0.02%	<0.02%
Sulfate	≤0.01%	<0.01%
Arsenic	≤0.0002%	<0.0002%
Residue on Ignition	≤0.1%	0.02%
Heavy metals	≤0.001%	<0.001%
Reducing on Ignition	≤0.10%	0.03%
Loss on Drying	≤0.5%	0.17%
Assay	98.0-102.0%	100.4%
Escherichia Coli	Negative	Negative
Salmonella	Negative	Negative
Bacteria Endotoxins	Conforms	Conforms

Mannitol is a diuretic medication, used to remove extra fluid from your bloodstream, and to increase urine output. Mannitol is used along with certain chemotherapy drugs, to prevent kidney damage. It may also be used to reduce fluid pressure in the brain for patients with brain cancers.